NHS Warning: Potential Complications from Diabetes Medication (2026)

Diabetes Medication Complications: NHS Issues Urgent Warning

The NHS has issued a critical alert to UK patients taking a commonly prescribed diabetes medication, dapagliflozin, urging them to seek immediate medical attention if they experience any of three specific symptoms. These symptoms could indicate serious health complications.

Dapagliflozin, sold under the brand name Forxiga, is primarily used to manage type 2 diabetes but is also prescribed for heart failure and chronic kidney disease. While its exact usage statistics are unavailable, it is one of the more expensive medications, with the NHS allocating approximately £300 million annually for it in England alone.

Dapagliflozin is also available in combination with other diabetes treatments, such as Xigduo (dapagliflozin with metformin) and Qtern (dapagliflozin with saxagliptin). However, the NHS warns that, like all medications, dapagliflozin can cause side effects.

The NHS outlines the following symptoms that may indicate serious complications:

  1. Dehydration: Experiencing a very dry or sticky mouth, feeling extremely thirsty, sleepy or tired, urinating very little, and having a fast heartbeat.
  2. Urinary Tract Infection (UTI): A high temperature or feeling hot or cold, a burning sensation when urinating, back or side pain, or blood in the urine.
  3. Fournier's Gangrene: Severe pain, tenderness, redness, or swelling in the groin or perineal area, accompanied by a high temperature or feeling unwell.

The NHS strongly advises patients to take these symptoms seriously and seek medical attention promptly to prevent potential health risks associated with dapagliflozin.

NHS Warning: Potential Complications from Diabetes Medication (2026)
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